Stem Cell Engineering Group - Publications
2005 – 2004
Edenhofer, F & M. Peitz. CREating designer cells. (2005) in press.
Murakami, M, T. Ichisaka, M. Maeda, N. Oshiro, K. Hara, F. Edenhofer, H. Kiyama, K. Yonezawa & S. Yamanaka. mTOR is essential for Proliferation and Growth in Early Mouse Embryos and Embryonic Stem Cells. Mol. Cell. Biol. 24 (2004) 6710-6718.
Haupt, S. (2004) Analyse der Cre Protein-Transduktion in ES-Zell-abgeleiteten neuralen Vorläufern, University of Cologne (Diploma thesis).
invited papers:
Edenhofer, F. Modulating Stem Cell Properties by Protein Transduction (Feb 2005), Banff, Canada, Keystone Symposium on Molecular Regulation of Stem Cells.
Edenhofer, F. Fusion proteins in stem cell research (Sep 2004) London, Int. Symposium in Stem Cell Repair and Regeneration.
Edenhofer, F. Manipulating Pluripotent Cells by Protein Transduction (Sep 2004) Honolulu, USA, 13th Conference of the Int. Society of Differentiation.
2003 – 2000
Peitz, M., K. Rajewsky, O. Brüstle & F. Edenhofer. Direct delivery of biologically active proteins into cells: protein transduction as a tool for genomic manipulations in mammalian cells. Eur. J. Cell. Biol. 82 Suppl.53 (2003) 36.
Badorf, M., F. Edenhofer, V. Dries, S. Kochanek & G. Schiedner. Efficient in vitro and in vivo excision of floxed sequences with a high-capacity adenoviral vector expressing Cre recombinase. Genesis 33 (2002) 119-124.
Peitz, M., K. Pfannkuche, K. Rajewsky & F. Edenhofer. Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes. Proc. Natl. Acad. Sci. USA 99 (2002) 4489-4494.
Edenhofer F., M. Peitz, K. Pfannkuche & K. Rajewsky. Recombinase fusion protein with enhanced cellular uptake. (2002) EP Nr. 020054680.
Wunderlich, F.T., H. Wildner, K. Rajewsky & F. Edenhofer. New variants of inducible Cre recombinase: a novel mutant of Cre-PR fusion protein exhibits enhanced sensitivity and an expanded range of inducibility. Nucleic Acids Res. 29 (2001) e47.
Edenhofer, F., F.T. Wunderlich & K. Rajewsky. Mutationen kryptischer Spleißstellen in Cre und Cre-Fusionsproteinen zur Verbesserung der Expression und Induzierbarkeit. (2000) EP Nr. 00114622.4-2105.
invited papers:
Edenhofer, F. Engineering stem cells for neural repair (Sep 2003), Dresden, 5th Meeting DFG SPP1129 Embryonic and Somatic Stem Cells.
Edenhofer, F. Direct delivery of biologically active proteins into cells: protein transduction as a tool for genomic manipulations in mammalian cells (Mar 2003), Bonn, Symposium of the German Society for Cell Biology.
1999 – 1995
*Rieger, R., *F. Edenhofer, C. I. Lasmézas & S. Weiss. The human 37-kDa laminin receptor precursor interacts with the prion protein in eucaryotic cells. Nature Med. 3 (1997) 1383-1388. *authors contributed equally
Edenhofer, F., S. Weiss, E.-L. Winnacker & M. Famulok. Chemistry and Molecular Biology of Transmissible Spongiform Encephalopathies. Angew. Chem. Int. Ed. Eng. 36 (1997) 1674-1694.
Edenhofer, F., R. Rieger, M. Famulok, W. Wendler, S. Weiss & E.-L. Winnacker. Prion Protein PrPc interacts with Molecular Chaperones of the Hsp60 Family. J. Virol. 70 (1996) 4724-4728.
Weiss, S., R. Rieger, F. Edenhofer, E. Fisch & E.-L. Winnacker. Recombinant prion protein rPrP27-30 from the Syrian Golden Hamster reveals protease K sensitivity. Biochem. Biophys. Res. Commun. 219 (1996) 173-179.
Weiss, S., M. Famulok, F. Edenhofer, Y.-H. Wang, I.M. Jones, M. Groschup & E.-L. Winnacker. Overexpression of Active Syrian Golden Hamster Prion Protein PrPc as a Glutathione S-Transferase Fusion in Heterologous Systems. J. Virol. 69 (1995) 4776-4783.
Weiss, S., F. Edenhofer, R. Rieger & E.-L. Winnacker. Chaperones capable of binding to Prion Proteins and distinguishing the isoforms PrPc and PrPSc. EP - 96 107 677.5.
Weiss, S., F. Edenhofer, R. Rieger & E.-L. Winnacker. Pharmaceutical Compositions comprising a soluble Laminin Receptor Precursor or a Compound which blocks the Interaction of the Laminin Receptor Precursor and PrPSc or PrPc. B 1419 EP.
